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Tirzepatide enhances weight loss with sustained treatment but discontinuation leads to weight regain
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Those discontinuing GLP-1 medications rapidly regained weight
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Adults with obesity using tirzepatide maintain 'remarkable' weight loss at 88 weeks
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How Much Weight Comes Back After You Stop Using a Weight-Loss Drug?
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Trajectory of weight regain after cessation of GLP-1 receptor agonists: a systematic review and meta-regression
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Tirzepatide for the Maintenance of Body Weight Reduction: Rationale, Design, and Baseline Characteristics of SURMOUNT‐MAINTAIN - Horn - 2025 - Obesity
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Weight regain after the withdrawal of tirzepatide (Zepbound) may wipe out many of the cardiometabolic gains made during weight loss, a post-hoc analysis of the SURMOUNT-4 trial indicated. Read more at: https://www.medpagetoday.com/endocrinology/obesity
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