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retatrutide is a novel triple agonist peptide at the glucagon receptor, GIP receptor, and GLP 1 receptor. 22 24% weight loss at 48 weeks with a similar tolerability profile to #tirzepatide. @LillyPad #medtwitter #endotwitter The promise and peril of GLP 1 agonists: What we do (and don't) know as of August 2024 Structure Based Discovery of Orthosteric Non Peptide GLP 1R Agonists via Integrated Virtual Screening and Molecular Dynamics[v1] Preprints.org Zepbound How It Works: Dual GLP 1 GIP Action Appetite Off Week 1
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