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Only a few week old (2026 jan 22) systematic review revealed that GLP-1 agonists have the greatest benefit for younger non-diabetic female patients. https://diabetesjournals.org/care/article/48/2/292/157724/Efficacy -of-GLP-1-Receptor-Agonists-on-Weight
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Among adults treated with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for weight loss, efficacy was greater in women than men, but similar across age, race, ethnicity, baseline body mass index, and hemoglobin
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