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Denaturing SEC-MS Analysis of High Molecular Weight Impurities in the GLP-1a Lipopeptides Semaglutide and Tirzepatide
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SURPASS‑EARLY evaluated starting tirzepatide early in type 2 diabetes vs. conventional step-therapy. In adults with early T2D on metformin, tirzepatide produced larger 2‑year reductions in HbA1c, weight, and waist circumference than intensified
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