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surmount-1 tirzepatide obesity nejm 2022 weight loss percent SURMOUNT-1 (NEJM 2022) tested tirzepatide — a dual GIP/GLP-1 receptor agonist — in 2,539 adults with obesity and achieved up to 20.9% mean weight loss at the highest dose. 57% of participants

Marsoni M251S
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People without type 2 diabetes (T2D) who have already lost weight using various methods, including a different GLP 1, can still achieve further weight loss by starting tirzepatide, new real world data from a Mounjaro (Tirzepatide) Injection 12.5 mg 0.5 mL Syringes How to Wean Off Tirzepatide: Safe Discontinuation Guide Fella Health Why Tirzepatide Doesn't Work for Some People: Causes and Solutions Fella Health
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4.3 ★★★★★
Based on 1516 reviews
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Verified Purchase
Tina Taylor
Pawtucket, US
★★★★★ 3
Ok
Ok
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 6, 2026
E
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Elaina rice
Carnegie, US
★★★★★ 5
Dog loves it! For tough chewers for sure
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Dog absolutely loves it, he’s super rough on all of his toys they usually last about 10 minutes bore they are torn to shreds. It’s lasting through his chewing so I’m happy. It’s also super cute.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 9, 2026
M
Verified Purchase
miriana
Bozeman, US
★★★★★ 5
Loch Yes
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Cute toy, dog really likes it. I had my doubts when I pulled it out, and honestly so did she, but the soft part bounces, so that got her going. We've had it for about a week. My dog is ~70 lbs and a moderate chewer, and this monster still gets regular play and is holding up well.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 18, 2026
Z
Verified Purchase
zee
Lake Worth, US
★★★★★ 5
Great toys for aggressive chewers
Size: Medium/Large, Color: Turkey Day Drumstick - Large
These are great toys they last a while they are destroyed after a while but both dogs are aggressive chewers but they last about a year and a half. And they are go to toys they have one that is a shark mouth and they love it I have bought 4. (two of them the pups lost ).
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 20, 2025
A
Verified Purchase
Anjelica
Lexington, US
★★★★★ 4
Durable and Fun, Just Gets a Bit Rough
Size: Medium/Large, Color: Chopper - Large
This is a really good toy overall, especially if you have dogs that love to chew. My dogs were immediately into it—they play with it nonstop, toss it around, and stay entertained for a while, which I love. It definitely holds up better than most toys we’ve tried. The only reason I’m giving it 4 stars instead of 5 is because over time it does start to fray a bit and gets a little rough, especially with heavy chewing. It’s not completely indestructible, but it still lasts longer than a lot of other toys. Overall, still a great buy and I would recommend it if your dogs need something tough but fun!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 4, 2026

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