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University of Pennsylvania researchers analyzed over 400,000 Reddit posts from nearly 70,000 users across five years and found that semaglutide and tirzepatide users are reporting menstrual irregularities and temperature complaints like chills
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A study in Nature Health analyzes Reddit posts between 2019 and 2025 that mentioned semaglutide or tirzepatide and finds a spectrum of associated reported side effects extending beyond the commonly known safety
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