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GLP-1 is made in your gut. So when you are on a GLP-1 medication and something isn't working, the gut is usually where I look first. Side effects. Plateaus.
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GLP-1 is produced by specialized cells in the intestinal lining called L-cells. These cells respond to signals from the gut microbiome. Certain beneficial bacteria produce compounds called short-chain fatty acids, which help
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Rebalancing the Gut: Glucagon-Like Peptide-1 Agonists as a Strategy for Obesity and Metabolic Health
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Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice
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