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The Rise of Oral Obesity Therapies: Semaglutide and Orforglipron
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orforglipron
20.11
Head-to-head trial shows Eli Lilly's oral GLP-1 orforglipron outperforms oral semaglutide
25.68
New GLP-1 pill orforglipron outperforms oral semaglutide in yearlong diabetes trial
27.23
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Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial
29.19
In a phase III trial, orforglipron yielded better HbA1c reduction compared with oral semaglutide at 52 weeks. Gastrointestinal side effects were more common with orforglipron, leading to more treatment discontinuations. Read more
21.75
A clinical trial for diabetes that pit orforglipron, a diabetes and weight-loss pill developed by Eli Lilly, against oral semaglutide, made by Novo Nordisk, suggests the former pill may have the edge
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