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moa of glp 1 Mechanism of action of GLP-1 [25]
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Pancreas and Not Gut Mediates the GLP 1 Induced Glucoincretin Effect ScienceDirect GLP 1 receptor agonists How Wegovy, Ozempic, and Mounjaro work The data just dropped and retatrutide is rewriting what's possible in obesity medicine. TRIUMPH 1 just released Phase 3 results, and the numbers are unlike anything we've seen from a medication: Everyone's talking about Ozempicbut your body already has a built in appetite regulating system: it's called GLP 1. This powerful hormone tells your brain you're full, helps reduce cravings, stabilizes blood sugar, and even boosts
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4.1 ★★★★★
Based on 1020 reviews
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★★★★★ 5
A forerunner to Dirty Harry and Lee Marvin shining...
If you liked "The Getaway" or "Dirty Harry", then meet their forerunner.
"Point Blank" is explosive, fast-paced, and still the acting is there.
Good acting that is.
Lee Marvin is at his best. Angie Dickinson. in her strong performance, is as beautiful as ever. Keenan Wynn and Carroll O'Connor play their parts to the hilt and it truly shows. John Vernon (who was The Mayor in "Dirty Harry") plays a slimy type with diligence and very believable.
Add the killing pace of the entire picture, and you have a hot item, as sharp and cutting as "Film Noir" can be.
Yes, because this is still a "Film Noir", despite the fact that it was filmed in Color and in the mid-sixties.
John Boorman ("Hell in the Pacific", "Deliverance" and "The Emerald Forest"), skillfully "color coded" the entire movie, bringing it from absolute colors at the beginning, to more red-tinted ones towards the end.
The only difference from a true "Film Noir" is its fast-paced storyline, that would lead us to movies as I have mentioned above.
Marvin's minimalistic acting, but forceful presence, is enough to fill every frame of the movie with tension, action and complete mayhem.
Compare him in "The Dirty Dozen" and "The Big Red One" and you will see what I mean.
A big plus was the release on DVD. An excellent transfer with a sharp picture resolution, a clearcut sound, make it a very enticing experience to watch it at home.
This is not just a Highly Recommended title. It is simply a Must!
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Reviewed in the United States on April 20, 2007
★★★★★ 5
Whiter teeth with out the trays
Size: 3.8 Ounce (Pack of 1)
Love this toothpaste! My teeth are a lot whiter and brighter. Doesn’t leave a bad taste in my mouth. Highly recommend this product.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 24, 2026
★★★★★ 5
smile time!!
Size: 3.8 Ounce (Pack of 1)
Love the whiteness! Works in a few weeks!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 8, 2026
★★★★★ 5
Works for removing coffee stains
Size: 3.8 Ounce (Pack of 1)
quit smoking after 25 years. I have been more than 50 days now without a cigarette and my coffee intake has decreased by 99%. I only drink one cup now in the morning. I've used this before and it worked well. However, I had such bad habits, I could never stay on top of it. Well, I started using again just 4 or 5 days ago. And I have noticed a huge difference already. And now I have changed my lifestyle, I feel that I will actually be able to get a better outcome. So far it's working really well to remove those coffee and nicotine cigarette stains. I have been to the dentist since I quit cigarettes. I've got a few cavities that I will be getting fixed in two weeks. So i'm trying to whiten between now and then. I didn't want to use anything too harsh. This does not make my teeth more sensitive.Some whitening toothpastes can increase my sensitivity. Although i'm not a fan of fluoride. I will use fluoride free toothpaste with hydroxyapatite on a regular basis..I just use this as needed. It does produce good results if you, in fact, are really trying to remove those coffee stains. But if you don't change your habits, it only works so much. Also, it's probably gonna work a whole lot better If you have an electric toothbrush. You're just not gonna get the same results using a regular toothbrush, at least not as fast.
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Reviewed in the United States on March 10, 2026
★★★★★ 4
Good product but packaging not so great
Size: 3.8 Ounce (Pack of 1)
I absolutely love this toothpaste and it works great. My only problem is I have had two separate tubes leak everywhere in the box before even opening them. Two brand new tubes of toothpaste ruined while in the box. Such a waste of money, and I still had to buy more toothpaste.
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Reviewed in the United States on May 20, 2026
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