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Tirzepatide for the treatment of obesity: Rationale and design of the SURMOUNT clinical development program - Roux - 2023 - Obesity
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![In an earlier analysis of the SURMOUNT-1 trial, tirzepatide (a dual glucose-dependent insulinotropic polypeptide [GIP] and glucagon-like peptide-1 [GLP-1] receptor agonist) was shown to provide substantial and sustained reductions in body weight](https://lookaside.instagram.com/seo/google_widget/crawler/?media_id=3585945231426876830)
In an earlier analysis of the SURMOUNT-1 trial, tirzepatide (a dual glucose-dependent insulinotropic polypeptide [GIP] and glucagon-like peptide-1 [GLP-1] receptor agonist) was shown to provide substantial and sustained reductions in body weight
29.19
SURMOUNT-1 Trial
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Tirzepatide and blood pressure reduction: stratified analyses of the SURMOUNT-1 randomised controlled trial
21.13
Tirzepatide on ingestive behavior in adults with overweight or obesity: a randomized 6-week phase 1 trial
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A 72-week trial compared the two leading GLP-1 medications in adults with obesity (no diabetes). The results: ✓ Tirzepatide: 20.2% weight loss ✓ Semaglutide: 13.7% weight loss But weight loss isn't the
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The SURMOUNT-MAINTAIN trial will help answer the question of what to do with the obesity medication dose to maintain weight loss long-term
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