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67,000 people on semaglutide (Wegovy) or tirzepatide (Mounjaro). 410,198 Reddit posts. Analysed by the University of Pennsylvania and published in Nature Health, April 2026. 43.5% reported at least one side effect. The
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My first injection (almost one year ago) -vs- this morning. SW 250, CW 170. I've been off semaglutide for a few months. As I've stopped the meds, I've increased my protein intake
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University of Pennsylvania researchers analyzed over 400,000 Reddit posts from nearly 70,000 users across five years and found that semaglutide and tirzepatide users are reporting menstrual irregularities and temperature complaints like chills
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A large-scale analysis of Reddit data identifies symptoms—including fatigue and menstrual changes—frequently missed in clinical trials. These real-world patient insights highlight a broader spectrum of physiological responses to semaglutide and
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AI study of Reddit posts reveals possible new side effects of weight loss drugs
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